Semaglutide Dosage Chart: Wegovy, Ozempic and Pill Doses From the Label

Written by Dr. Diana Munteanu. Updated October 22, 2026.

Semaglutide always starts at a low dose and steps up every four weeks (or every 30 days for the pills) to limit nausea. The weekly Wegovy injection goes 0.25 → 0.5 → 1 → 1.7 → 2.4 mg over 16 weeks; Ozempic goes 0.25 → 0.5 mg, then up to 1 mg and 2 mg if needed; the daily Wegovy pill goes 1.5 → 4 → 9 → 25 mg; and Ozempic tablets go 1.5 → 4 mg, then 9 mg if needed. The charts below come from the FDA-approved labels.

This guide covers brand-name, FDA-approved products only. Your prescriber decides your dose and may move more slowly. It does not cover compounded vials, which have no approved dosing; see the warning at the end.

Missed a Wegovy shot? Take it if your next dose is more than 2 days away; otherwise skip it and take the next one on schedule. If you miss two weeks or more, ask your prescriber whether to restart at a lower dose.

Take the pill first thing in the morning on an empty stomach with up to 4 ounces of plain water, then wait at least 30 minutes before eating, drinking or taking other medicines.

Missed an Ozempic shot? Take it within 5 days of the missed day. If more than 5 days have passed, skip it and take the next dose on your usual day.

Ozempic tablets follow the same empty-stomach rules as the Wegovy pill. The older Rybelsus strengths of 3, 7 and 14 mg are being replaced by these new strengths.

Nausea, vomiting and diarrhea are most common in the first weeks and right after each increase. Stepping up gradually gives the gut time to adapt. If side effects are hard to manage, prescribers often keep you at the current dose for longer rather than pushing on. See our semaglutide side effects guide and how long semaglutide stays in your system.

Charts that convert "units" to milligrams are made for compounded vials, whose concentration varies from one pharmacy to another. FDA has linked hospitalizations to dosing errors with these products. Brand-name pens and tablets are pre-measured, so no conversion is needed. Read more in compounded semaglutide reviews and why a microdosing semaglutide chart isn't a dosing plan.

For what to expect at each step of the chart, read how long semaglutide takes to work, a week-by-week guide to appetite, blood sugar and weight changes.

One thing this chart cannot do is convert a semaglutide dose into a tirzepatide dose; there is no equivalence, and tirzepatide starts at 2.5 mg for everyone. Our guide to switching from semaglutide to tirzepatide explains how the change is actually made.

Each step up the ladder brings a short wave of side effects, and fatigue is one that people rarely expect. The causes, timeline and fixes are covered in does semaglutide make you tired; if a step knocks you flat, staying longer on the current dose is an option the label allows.

Every semaglutide product starts low and climbs: Wegovy to 2.4 mg (or 7.2 mg HD) weekly by week 17, the Wegovy pill to 25 mg daily by day 91, Ozempic to 0.5–2 mg weekly, and Ozempic tablets to 4–9 mg daily. Follow your prescription, not a forum chart. For results by dose, see semaglutide for weight loss, and for pill versus injection, see oral semaglutide vs tablets vs pills.